(a) Chemical substances and significant new uses subject to reporting.
(1) The benzidine-based chemical substances listed in Table 1 and Table 2 of this section are subject to reporting under this section for the significant new uses described in paragraph (a)(2) of this section.
Table 1 - Benzidine-Based Chemical Substances
| CAS or accession No. | C.I. name | C.I. No. | Chemical name |
|---|---|---|---|
| 117-33-9 | Not available | Not available | 1,3-Naphthalenedisulfonic acid, 7-hydroxy-8-[2-[4'-[2-(4-hydroxyphenyl)diazenyl][1,1'-biphenyl]-4-yl]diazenyl]- |
| 65150-87-0 | Not available | Not available | 1,3,6-Naphthalenetrisulfonic acid, 8-hydroxy-7-[2-[4'-[2-(2-hydroxy-1-naphthalenyl)diazenyl][1,1'- biphenyl]-4-yl]diazenyl]-, lithium salt (1:3) |
| 68214-82-4 | Direct Navy BH | 22590 | 2,7-Naphthalenedisulfonic acid, 5-amino-3-[2-[4'-[2-(7-amino-1-hydroxy-3-sulfo-2- naphthalenyl)diazenyl][1,1'-biphenyl]-4- yl]diazenyl]-4-hydroxy-, sodium salt (1:2) |
| 72379-45-4 | Not available | Not available | 2,7-Naphthalenedisulfonic acid, 4-amino-5- hydroxy-3-[2-[4'-[2-[2-hydroxy-4-[(2- methylphenyl)amino]phenyl]diazenyl][1,1'- biphenyl]-4-yl]diazenyl]-6-(2-phenyldiazenyl)- |
| Accession No. 21808 CAS No. CBI (NA) |
CBI | CBI | 2,7-Naphthalenedisulfonic acid, 4-amino-5- hydroxy [[[(substituted phenylamino)] substituted phenylazo] diphenyl]azo-, phenylazo-, disodium salt. (generic name) |
| Accession No. 24921 CAS No. |
CBI | CBI | 4-(Substituted naphthalenyl )azo diphenylyl azo-substituted carbopolycycle azo benzenesulfonic acid, sodium salt. (generic name) |
| Accession No. 26256 CAS No. CBI (NA) |
CBI | CBI | 4-(Substituted phenyl)azo biphenylyl azo- substituted carbopolycycloazo benzenesulfonic acid, sodium salt. (generic name) |
| Accession No. 26267 CAS No. CBI (NA) |
CBI | CBI | 4-(Substituted phenyl)azo biphenylyl azo - substituted carbopolycycle azo benzenesulfonic acid, sodium salt. (generic name) |
| Accession No. 26701 CAS No. CBI (NA) |
CBI | CBI | Phenylazoaminohydroxynaphthalenylazobiphenylazo substituted benzene sodium sulfonate. (generic name). |
Table 2 - Benzidine-Based Chemical Substances
| CAS No. | C.I. name | C.I. No. | Chemical name |
|---|---|---|---|
| 92-87-5 | Benzidine | Not available | [1,1′-Biphenyl]-4,4′-diamine. |
| 531-85-1 | Benzidine · 2HCl | Not available | [1,1′-Biphenyl]-4,4′-diamine, dihydrochloride. |
| 573-58-0 | C.I. Direct Red 28 | 22120 | 1- Naphthalenesulfonic acid, 3,3′-[[1,1′-biphenyl]-4,4′-diylbis(azo)]bis[4-amino-, disodium salt. |
| 1937-37-7 | C.I. Direct Black 38 | 30235 | 2,7-Naphthalenedisulfonic acid, 4-amino-3-[[4′-[(2,4-diaminophenyl) azo][1,1′-biphenyl]-4- yl]azo]-5-hydroxy-6-(phenylazo)-, disodium salt. |
| 2302-97-8 | C.I. Direct Red 44 | 22500 | 1-Naphthalenesulfonic acid, 8,8′-[[1,1′-biphenyl]-4,4′-diylbis(azo)]bis[7-hydroxy-, disodium salt. |
| 2429-73-4 | C.I. Direct Blue 2 | 22590 | 2,7-Naphthalenedisulfonic acid, 5-amino-3-[[4′-[(7-amino-1-hydroxy-3-sulfo-2-naphthalenyl)azo][1,1′-biphenyl]-4-yl]azo]-4-hydroxy-, trisodium salt. |
| 2429-79-0 | C.I. Direct Orange 8 | 22130 | Benzoic acid, 5-[[4′-[(1-amino-4-sulfo-2-naphthalenyl) azo][1,1′-biphenyl]-4-yl]azo]-2- hydroxy-, disodium salt. |
| 2429-81-4 | C.I. Direct Brown 31 | 35660 | Benzoic acid, 5-[[4′-[[2,6-diamino-3-[[8-hydroxy-3,6-disulfo-7-[(4-sulfo-1-naphthalenyl)azo]-2- naphthalenyl]azo]-5-methylphenyl]azo][1,1′- biphenyl]-4-yl]azo]-2-hydroxy-, tetrasodium salt. |
| 2429-82-5 | C.I. Direct Brown 2 | 22311 | Benzoic acid, 5-[[4′-[(7-amino-1-hydroxy-3-sulfo-2-naphthalenyl) azo][1,1′-biphenyl]-4-yl]azo]-2-hydroxy-, disodium salt. |
| 2429-83-6 | Direct Black 4 | 30245 | 2,7-Naphthalenedisulfonic acid, 4-amino-3-[[4′-[(2,4-diamino-5-methylphenyl)azo][1,1′-biphenyl]-4-yl]azo] -5-hydroxy-6-(phenylazo)-, disodium salt. |
| 2429-84-7 | C.I. Direct Red 1 | 22310 | Benzoic acid, 5-[[4′-[(2-amino-8-hydroxy-6-sulfo-1-naphthalenyl)azo][1,1′-biphenyl]-4-yl]azo]-2-hydroxy-, disodium salt. |
| 2586-58-5 | C.I. Direct Brown 1:2 | 30110 | Benzoic acid, 5-[[4′-[[2,6-diamino-3-methyl-5-[(4-sulfophenyl)azo]phenyl]azo][1,1′-biphenyl]-4- yl]azo]-2-hydroxy-, disodium salt. |
| 2602-46-2 | C.I. Direct Blue 6 | 22610 | 2,7-Naphthalenedisulfonic acid, 3,3′-[[1,1′-biphenyl]-4,4′-diylbis(azo)]bis[5-amino-4-hydroxy-, tetrasodium salt. |
| 2893-80-3 | C.I. Direct Brown 6 | 30140 | Benzoic acid, 5-[[4′-[[2,4-dihydroxy-3-[(4-sulfophenyl) azo]phenyl]azo][1,1′-biphenyl]-4- yl]azo]-2-hydroxy-, disodium salt. |
| 3530-19-6 | C.I. Direct Red 37 | 22240 | 1,3-Naphthalenedisulfonic acid, 8-[[4′-[(4-ethoxyphenyl)azo][1,1′-biphenyl]-4-yl]azo]-7-hydroxy-, disodium salt |
| 3567-65-5 | C.I. Acid Red 85 | 22245 | 1,3-Naphthalenedisulfonic acid, 7-hydroxy-8-[[4′-[[4-[[(4-methylphenyl)sulfonyl]oxy]phenyl]azo][1,1′-biphenyl]-4-yl]azo]-, disodium salt. |
| 3626-28-6 | C.I. Direct Green 1 | 30280 | 2,7-Naphthalenedisulfonic acid, 4-amino-5-hydroxy-3-[[4′-[(4-hydroxyphenyl)azo][1,1′- biphenyl]-4- yl]azo]-6-(phenylazo)-, disodium salt. |
| 3811-71-0 | C.I. Direct Brown 1 | 30045 | Benzoic acid, 5-[[4′-[[2,4-diamino-5-[(4-sulfophenyl) azo]phenyl]azo][1,1′ biphenyl]-4- yl]azo]-2-hydroxy-, disodium salt. |
| 4335-09-5 | C.I. Direct Green 6 | 30295 | 2,7-Naphthalenedisulfonic acid, 4-amino-5-hydroxy-6-[[4′-[(4-hydroxyphenyl)azo][1,1′-biphenyl]-4- yl]azo]-3-[(4-nitrophenyl)azo]-, disodium salt. |
| 6358-80-1 | C.I. Acid Black 94 | 30336 | 2,7-Naphthalenedisulfonic acid, 4-amino-5-hydroxy-3-[[4′-[[4-hydroxy-2-[(2- methylphenyl)amino]phenyl]azo] [1,1′- biphenyl]-4-yl]azo]-6-[(4-sulfophenyl) azo]-, trisodium salt. |
| 6360-29-8 | C.I. Direct Brown 27 | 31725 | Benzoic acid, 5-[[4′-[[4-[(4-amino-7-sulfo-1-naphthalenyl)azo]-6-sulfo-1-naphthalenyl]azo][1,1′-biphenyl]-4-yl] azo]-2- hydroxy-, trisodium salt. |
| 6360-54-9 | C.I. Direct Brown 154 | 30120 | Benzoic acid, 5-[[4′-[[2,6-diamino-3-methyl-5-[(4-sulfophenyl)azo]phenyl] azo][1,1′-biphenyl]-4-yl]azo]-2- hydroxy-3-methyl-, disodium salt. |
| 8014-91-3 | C.I. Direct Brown 74 | 36300 | Benzoic acid, 3,3′-[(3,7-disulfo-1,5-naphthalenediyl)bis [azo(6-hydroxy-3,1-phenylene)azo[6(or7)-sulfo-4,1-naphthalenediyl]azo[1,1′-biphenyl]-4,4′-diylazo]]bis[6-hydroxy-, hexasodium salt. |
| 16071-86-6 | C.I. Direct Brown 95 | 30145 | Cuprate(2-), [5-[[4′-[[2,6-dihydroxy-3-[(2-hydroxy-5-sulfophenyl)azo]phenyl] azo][1,1′- biphenyl]-4-yl]azo]-2-hydroxybenzoato(4-)]-, disodium salt. |
(2) The significant new uses are:
(i) For each of the chemical substances listed in Table 2 of this section, any use other than use as a reagent to test for hydrogen peroxide in milk; a reagent to test for hydrogen sulfate, hydrogen cyanide, and nicotine; a stain in microscopy; a reagent for detecting blood; an analytical standard; and, additionally for Colour Index (C.I.) Direct Red 28 (Congo Red) (CAS No. 573-58-0), an indicator dye.
(ii) For the chemical substances listed in Table 1 of this section: Any use.
(b) Specific requirements. The provisions of subpart A of this part apply to this section except as modified by this paragraph (b).
(1) Revocation of certain notification exemptions. The provisions of § 721.45(f) do not apply to this section. A person who imports or processes a chemical substance identified in paragraph (a)(1) of this section as part of an article for a significant new use described in paragraph (a)(2) of this section is not exempt from submitting a significant new use notice.
(2) [Reserved]
[79 FR 77909, Dec. 29, 2014]